EHRN: COVID-Vaccinated Mothers Less Likely to Have Premature Birth Than Unvaccinated Mothers

EHRN: COVID-Vaccinated Mothers Less Likely to Have Premature Birth Than Unvaccinated Mothers

Abstract: Preterm birth and low birth weight are less prevalent among babies born to mothers who received the SARS-CoV-2 vaccine.

In a previous EHRN study, we found mothers that tested positive for COVID-19 experienced greater rates of preterm birth and low birth weight than mothers that tested negative for COVID-19. Other early studies of COVID-19 vaccination in pregnancy point to the vaccine’s safety.1 With the increase in availability of the COVID-19 vaccine, we analyzed a large population of COVID-vaccinated mothers’ risk of preterm birth or low birth weight compared to babies born to unvaccinated mothers. Nearly all women who were vaccinated in their first trimester have not yet given birth; therefore, this study looked only at second and third trimester vaccination outcomes.

The data showed that 82 of 2,399 (3.4%) babies born to vaccinated mothers were preterm, while 10,154 of 104,838 (9.7%) babies born to unvaccinated mothers were preterm. 64 of 2,399 (2.7%) babies born to vaccinated mothers had a low birth weight, and 7,839 of 104,838 (7.5%) of babies born to unvaccinated mothers had a low birth weight. CDC-reported baselines for preterm birth and low birth weight are 10% and 8.3%, respectively2,3.

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